Preventing Crohn's disease in people at high risk
Prevention of Crohns Disease in High-Risk Individuals
This study is looking at how changes in diet and lifestyle can help prevent Crohn's disease in people who have a family member with the condition, and it will provide personalized advice to help you make choices that could lower your risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11079567 on NIH RePORTER |
What this research studies
This research focuses on preventing Crohn's disease, a chronic inflammatory bowel condition, in individuals who are at high risk, such as those with a first-degree relative diagnosed with the disease. The study will explore how dietary and lifestyle changes can influence the development of Crohn's disease by examining specific biomarkers that indicate early signs of the condition. Participants will receive personalized risk assessments and counseling to help them make informed lifestyle choices aimed at reducing their risk of developing Crohn's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults over 21 years old who have a first-degree relative with Crohn's disease or carry genetic variants associated with the condition.
Not a fit: Patients who do not have a family history of Crohn's disease or relevant genetic markers may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly lower the incidence of Crohn's disease in high-risk individuals through effective prevention strategies.
How similar studies have performed: Previous research has shown promise in using lifestyle modifications to influence disease outcomes in similar populations, indicating that this approach may be effective.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Lopes, Emily Walsh — Massachusetts General Hospital
- Study coordinator: Lopes, Emily Walsh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.