Preventing cervical cancer in women with HIV and HPV in India
Secondary Cervical Cancer Prevention of Vulnerable Women with HPV and HIV Co-infection in India
This project offers HPV screening, nurse-led community support, and nutritional help to women in India living with HIV and HPV to lower the chance of cervical precancers.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-11172546 on NIH RePORTER |
What this research studies
You would receive regular HPV screening and follow-up care delivered locally by ASHA community health workers and nurses. The program combines emotional counseling, skill-building, stigma reduction, nutrition education, and protein-enriched food supplements to support immune and overall health. Researchers will monitor CD4 cell counts, body composition, mental health, and cervical screening results over time. The goal is to see whether these combined supports reduce precancerous cervical changes among women living with HIV.
Who could benefit from this research
Good fit: Women in India who are living with HIV and have HPV infection or are at high risk for HPV, and who can receive local HPV screening, counseling, and nutritional support, are ideal candidates.
Not a fit: Women without HIV or HPV, people with advanced diagnosed cervical cancer, or individuals who cannot access the local program sites are unlikely to benefit from this project.
Why it matters
Potential benefit: If successful, this could reduce precancerous cervical lesions and future cervical cancer risk while improving immune health and mental well‑being for women with HIV and HPV.
How similar studies have performed: The team’s prior R01 with 600 women showed improved CD4 counts, increased lean mass, and better mood and social support, and preliminary data suggested nutritional supplements may cut precancer risk by about 40%, so this builds on promising results.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Nyamathi, Adeline M — University of California-Irvine
- Study coordinator: Nyamathi, Adeline M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.