Preventing cervical cancer in women with HIV
Project 1-Preventing cervical cancer in HIV-infected women
['FUNDING_OTHER'] · INDIANA UNIVERSITY INDIANAPOLIS · NIH-10897812
This study is looking at new ways to help women with HIV in Kenya and Uganda get better cervical cancer screenings by using self-collected samples and other methods, while also exploring how certain harmful substances might affect their risk of developing cervical cancer.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | INDIANA UNIVERSITY INDIANAPOLIS (nih funded) |
| Locations | 1 site (INDIANAPOLIS, UNITED STATES) |
| Trial ID | NIH-10897812 on ClinicalTrials.gov |
What this research studies
This research focuses on improving cervical cancer screening methods for HIV-infected women in Kenya and Uganda, where cervical cancer rates remain high despite antiretroviral therapy. The project aims to evaluate the effectiveness of self-collected vaginal swabs for HPV DNA testing combined with visual inspection methods to detect precancerous conditions. Additionally, the study will investigate the role of aflatoxin, a carcinogenic substance, in increasing the risk of HPV infection and cervical cancer in these women. By understanding these factors, the research seeks to develop better prevention strategies for cervical cancer in this vulnerable population.
Who could benefit from this research
Good fit: Ideal candidates for this research are HIV-infected women living in Kenya or Uganda who are at risk for cervical cancer.
Not a fit: Patients who are not HIV-infected or those living outside of Kenya and Uganda may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective screening and prevention strategies for cervical cancer in HIV-infected women, potentially reducing cancer incidence and improving health outcomes.
How similar studies have performed: Previous research has shown that improved screening methods can significantly impact cancer detection rates, suggesting that this approach may also be effective.
Where this research is happening
INDIANAPOLIS, UNITED STATES
- INDIANA UNIVERSITY INDIANAPOLIS — INDIANAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BROWN, DARRON R — INDIANA UNIVERSITY INDIANAPOLIS
- Study coordinator: BROWN, DARRON R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: AIDS associated cancer, AIDS related cancer, Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus