Preventing cervical cancer in HIV-positive women in Mexico and Puerto Rico
CAMPO Central Laboratory Core
This research is all about helping women with HIV in Mexico and Puerto Rico stay healthy by testing new ways to find and treat cervical cancer, including better screening methods, probiotics to improve health, and a new vaccine, so they can have more options for care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11177203 on NIH RePORTER |
What this research studies
This research focuses on preventing cervical cancer among HIV-positive women in Mexico and Puerto Rico through three clinical studies. The first study will test new screening methods for detecting high-grade cervical lesions in 4,000 women. The second study will explore the effects of probiotics on the microbiota and their potential to help reverse lesions in 600 participants. The third study will assess a new therapeutic HPV vaccine's safety and effectiveness in treating cervical and anal lesions in 300 individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are HIV-positive women and men, particularly those at risk for cervical and anal high-grade lesions.
Not a fit: Patients who are HIV-negative or do not have any cervical or anal lesions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of cervical cancer in HIV-positive women.
How similar studies have performed: Previous research has shown promising results in using probiotics and therapeutic vaccines for similar conditions, indicating potential success for this approach.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Darragh, Teresa Marie — University of California, San Francisco
- Study coordinator: Darragh, Teresa Marie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.