Preventing Breast Cancer with Green Tea and Broccoli Sprouts
Combinatorial epigenetic-based prevention of breast cancer
['FUNDING_R01'] · UNIVERSITY OF ALABAMA AT BIRMINGHAM · NIH-11009548
This project explores how combining green tea and broccoli sprouts might help prevent a serious type of breast cancer.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ALABAMA AT BIRMINGHAM (nih funded) |
| Locations | 1 site (BIRMINGHAM, UNITED STATES) |
| Trial ID | NIH-11009548 on ClinicalTrials.gov |
What this research studies
This research looks at using a combination of green tea and broccoli sprouts to prevent a specific, aggressive type of breast cancer called estrogen receptor-negative (ER-) breast cancer. We've seen that these dietary components can work together to delay the start and slow the growth of this cancer, even at safe amounts. The project also explores how these dietary changes might affect our genes and even pass protective effects from one generation to the next. Understanding these effects could lead to new ways to prevent breast cancer for future generations.
Who could benefit from this research
Good fit: This research is relevant for individuals concerned about preventing estrogen receptor-negative breast cancer, especially those with a family history or higher risk.
Not a fit: Patients currently undergoing treatment for active breast cancer or those not at risk for estrogen receptor-negative breast cancer may not directly benefit from this prevention-focused approach.
Why it matters
Potential benefit: If successful, this research could offer a safe and effective dietary strategy to prevent a highly aggressive form of breast cancer, potentially even across generations.
How similar studies have performed: Previous work by this team has shown that combining green tea and broccoli sprouts can delay cancer initiation and impede progression in models, suggesting promise for this approach.
Where this research is happening
BIRMINGHAM, UNITED STATES
- UNIVERSITY OF ALABAMA AT BIRMINGHAM — BIRMINGHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TOLLEFSBOL, TRYGVE O — UNIVERSITY OF ALABAMA AT BIRMINGHAM
- Study coordinator: TOLLEFSBOL, TRYGVE O
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Breast Cancer, Breast Cancer Prevention, Breast Cancer Risk Factor, Cancer Treatment, Cancers