Preventing breast cancer related to childbirth
Targeted Prevention of Postpartum-Related Breast Cancer (PRBC)
This study is looking at how having a baby might raise the risk of breast cancer in women within five years after childbirth, and it’s exploring whether certain anti-inflammatory medications could help lower that risk by examining changes in breast tissue.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Jacksonville NIH-funded |
| Lab location | 1 site (Jacksonville, United States) |
| Project ID | NIH-11042754 on NIH RePORTER |
What this research studies
This research investigates the increased risk of breast cancer that can occur in women within five years after giving birth. It focuses on understanding how postpartum changes in breast tissue, particularly inflammation, may contribute to this risk. The study aims to explore the potential preventive effects of non-steroidal anti-inflammatory drugs (NSAIDs) in women who are at higher risk for postpartum-related breast cancer. By analyzing breast tissue samples and patient histories, the research seeks to identify biomarkers that could help predict and prevent breast cancer in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are women who have recently given birth and have a family history of breast cancer or other risk factors.
Not a fit: Patients who are not postpartum or do not have risk factors for breast cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new preventive strategies for women at risk of postpartum-related breast cancer.
How similar studies have performed: Previous research has indicated that NSAIDs may reduce breast cancer risk in women with benign breast disease, suggesting a promising avenue for this study.
Where this research is happening
Jacksonville, United States
- Mayo Clinic Jacksonville — Jacksonville, United States (Active)
Researchers
- Principal investigator: Sherman, Mark E — Mayo Clinic Jacksonville
- Study coordinator: Sherman, Mark E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.