Preventing bacterial infections after surgery

The BASIC trial: Improving implementation of evidence-based approaches and surveillance to prevent bacterial transmission and infection

NIH-funded research Dartmouth College · NIH-11098544

This project aims to find the best ways to stop serious bacterial infections from happening to patients after surgery.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDartmouth College NIH-funded
Lab location1 site (Hanover, United States)
Project IDNIH-11098544 on NIH RePORTER

What this research studies

Many patients face a risk of infection after surgery, which can lead to longer hospital stays and other serious problems. This project is looking for the most effective methods to reduce the spread of common bacteria like MRSA and others that cause these infections. Researchers will test different combinations of improved hand hygiene, better care for medical tubes, cleaner environments, and patient treatments to reduce bacteria on the skin. The goal is to identify a comprehensive approach that significantly lowers the chance of developing an infection after an operation.

Who could benefit from this research

Good fit: Patients who are undergoing surgery and are at risk for bacterial infections could potentially benefit from the improved practices developed through this project.

Not a fit: Patients not undergoing surgery or those not at risk for these specific bacterial infections would not directly benefit from this particular project.

Why it matters

Potential benefit: If successful, this work could significantly reduce the risk of serious infections for patients undergoing surgery, leading to safer recoveries and fewer complications.

How similar studies have performed: Previous efforts using multi-faceted approaches have shown significant reductions in surgical site infections caused by specific bacteria like S. aureus.

Where this research is happening

Hanover, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.