Preparing for pandemics caused by bunyaviruses and picornaviruses
Official title: Bunyavirus and Picornavirus Pandemic Pathogen Preparedness (BP4) Center
Funded at Vanderbilt University Medical Center · NIH-10863653 · Data updated 2026-11-12
This study is looking at how our immune system fights off certain viruses that can make people sick, and it's exploring new vaccines and treatments to help protect everyone from these viruses in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | August 20, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $38,056,004 |
| NIH project number | 1U19AI181979-01 |
| Project ID | NIH-10863653 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit include individuals at risk for infections caused by bunyaviruses and picornaviruses, such as those in endemic regions or with compromised immune systems.
✕Less likely to help
Patients who are not at risk for these specific viral infections or those with unrelated health conditions may not receive any benefit from this research.
What this research studies
This research focuses on understanding how the immune system responds to bunyaviruses and picornaviruses, which are significant public health threats. A team of experts will investigate various vaccine strategies and antibody therapies to create effective medical countermeasures against these viruses. By studying prototype pathogens, the research aims to develop broad strategies that can be applied to different viruses within these families. Patients may benefit from advancements in vaccines and treatments that could protect against future outbreaks.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective vaccines and therapies that protect against serious viral infections.
How similar studies have gone: Previous research has shown promise in developing vaccines and therapies for related viral families, indicating potential for success in this novel approach.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Crowe, James E — Vanderbilt University Medical Center
- Study coordinator: Crowe, James E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.