PrEP choices to better protect young women at reproductive health clinics in Kenya

Effectiveness of PrEP product choice on HIV prevention coverage among young women in Kenya seeking reproductive health services

NIH-funded research University of Alabama at Birmingham · NIH-11140972

This project compares daily pills, monthly injections, and vaginal rings to help young women visiting reproductive health clinics in Kenya stay protected from HIV.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-11140972 on NIH RePORTER

What this research studies

If you are a young woman using family planning or antenatal services in Kenya, you may be offered different HIV prevention options such as daily oral PrEP, a monthly dapivirine ring, or periodic injectable cabotegravir. Clinic staff will be trained and clinic systems organized to offer these choices as part of routine reproductive care and to help with follow-up. The team will track which products women start, how long they continue them, and whether offering a choice improves ongoing protection. The focus is on making prevention easier to use and better matched to women’s lives so fewer people stop using it.

Who could benefit from this research

Good fit: Young women (about 15–30 years old) attending participating reproductive health clinics in Kenya who are at risk for HIV and interested in using PrEP are ideal candidates.

Not a fit: Women who already have reliable HIV prevention through other means, who do not want to use PrEP products, or who have medical reasons they cannot use specific PrEP options may not benefit.

Why it matters

Potential benefit: If successful, this approach could help more young women stay continuously protected from HIV by offering longer-acting PrEP options that fit their needs.

How similar studies have performed: Oral PrEP has been proven to prevent HIV but many young women stop taking it, while recent trials show dapivirine rings and injectable cabotegravir can provide effective, longer-acting protection, so offering choice and clinic integration builds on that evidence.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.