Pregnancy and baby health for people with intellectual and developmental disabilities

Maternal and Infant Outcomes among Pregnant Women with Intellectual and Developmental Disability

NIH-funded research University of California, San Diego · NIH-11249642

This project looks at why pregnant people with intellectual and developmental disabilities have higher risks during pregnancy and for their babies using large health and birth records.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-11249642 on NIH RePORTER

What this research studies

Researchers will use large-scale hospital, birth, and administrative records to examine pregnancy and infant outcomes for people with intellectual and developmental disabilities like you. They will compare different IDD diagnoses (including autism) and use advanced statistical methods called causal mediation analyses to untangle how factors such as chronic health conditions, smoking, prenatal care, and pregnancy complications contribute to those risks. The team will quantify how much each factor explains the higher risks so they can point to specific targets for interventions. The goal is to identify practical places—such as improving prenatal care or managing chronic conditions—where changes could help mothers and infants.

Who could benefit from this research

Good fit: Pregnant people or those planning pregnancy who have an intellectual or developmental disability (including autistic people), particularly whose care and births are recorded in the administrative databases used (e.g., state hospital and birth records).

Not a fit: People without an IDD diagnosis or whose pregnancies occur outside the medical or birth records used (for example unrecorded home births or care completely outside the included regions) are unlikely to be included or directly benefit.

Why it matters

Potential benefit: If successful, this work could point to specific care changes or programs that reduce pregnancy and infant risks for people with intellectual and developmental disabilities.

How similar studies have performed: Previous studies have shown higher maternal and infant risks for people with IDD, but few have used large administrative data combined with causal mediation methods, so this approach is relatively novel.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autistic Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.