Predictors of Type 2 diabetes in children and teens

Predictors of Youth-Onset Type 2 Diabetes: UAB Clinical Center

NIH-funded research University of Alabama at Birmingham · NIH-11286641

This project follows children and teens through puberty to find the medical, social, and behavioral factors that make some develop type 2 diabetes.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-11286641 on NIH RePORTER

What this research studies

You would be followed over several years through puberty with regular clinic visits. The team will measure blood sugar, insulin responses, growth and development, and collect information about diet, activity, mental health, and social environment. Researchers will compare young people who stay healthy with those who develop prediabetes or type 2 diabetes to spot early changes. The goal is to identify which risk factors can be changed to prevent or delay diabetes.

Who could benefit from this research

Good fit: Ideal candidates are children and adolescents (preteen through teen years), especially those who are overweight or have a family history or other risk factors for type 2 diabetes.

Not a fit: Adults, very young children outside the enrolled age range, or people with type 1 diabetes are unlikely to benefit directly from participating.

Why it matters

Potential benefit: If successful, this work could help identify at-risk youth earlier and point to better ways to prevent or delay type 2 diabetes.

How similar studies have performed: Previous long-term studies in youth have identified risk patterns for type 2 diabetes, and this project builds on that work by focusing closely on changes that happen during puberty.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.