Predicting treatment risks in foregut cancers using modifiable factors
Official title: Using Modifiable Factors to Predict Risk of non-Guideline Concordant Treatment in Foregut Cancers: A Novel Implementation Science-based approach
Funded at University of Alabama at Birmingham · NIH-11159430 · Data updated 2026-11-12
This study is looking at how to help people with foregut cancers, like esophageal and pancreatic cancer, get the best treatment possible by finding out what makes it harder for some patients, especially based on their race or where they live, and creating tools to identify those who might need extra support.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project start | May 9, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $161,797 |
| NIH project number | 5K23MD018383-04 |
| Project ID | NIH-11159430 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with foregut cancers who may face barriers to receiving guideline-concordant treatment based on their race or geographic location.
✕Less likely to help
Patients with foregut cancers who are already receiving guideline-concordant treatment or those outside the targeted demographic may not benefit from this research.
What this research studies
This research focuses on foregut cancers, which include esophageal, gastric, liver, biliary, and pancreatic cancers, and aims to address the disparities in treatment access and adherence to evidence-based guidelines. By identifying modifiable barriers related to race and location, the project seeks to develop a risk prediction model and a screening tool to identify patients at risk of not receiving guideline-concordant therapy. The approach involves mixed methods research to ensure that the tools created are both clinically applicable and statistically valid, ultimately aiming to facilitate personalized interventions for at-risk patients.
Why it matters
Potential benefit: If successful, this research could significantly improve access to appropriate cancer treatments for underserved populations.
How similar studies have gone: Other research has shown success in addressing healthcare disparities through similar predictive modeling approaches, indicating potential for impactful outcomes in this area.
Where this research is happening
-
University of Alabama at Birmingham
Birmingham, United States Active
Researchers
- Principal investigator: Fonseca, Annabelle L — University of Alabama at Birmingham
- Study coordinator: Fonseca, Annabelle L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.