Predicting treatment risks in foregut cancers using modifiable factors

Using Modifiable Factors to Predict Risk of non-Guideline Concordant Treatment in Foregut Cancers: A Novel Implementation Science-based approach

['FUNDING_OTHER'] · UNIVERSITY OF ALABAMA AT BIRMINGHAM · NIH-11159430

This study is looking at how to help people with foregut cancers, like esophageal and pancreatic cancer, get the best treatment possible by finding out what makes it harder for some patients, especially based on their race or where they live, and creating tools to identify those who might need extra support.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF ALABAMA AT BIRMINGHAM (nih funded)
Locations1 site (BIRMINGHAM, UNITED STATES)
Trial IDNIH-11159430 on ClinicalTrials.gov

What this research studies

This research focuses on foregut cancers, which include esophageal, gastric, liver, biliary, and pancreatic cancers, and aims to address the disparities in treatment access and adherence to evidence-based guidelines. By identifying modifiable barriers related to race and location, the project seeks to develop a risk prediction model and a screening tool to identify patients at risk of not receiving guideline-concordant therapy. The approach involves mixed methods research to ensure that the tools created are both clinically applicable and statistically valid, ultimately aiming to facilitate personalized interventions for at-risk patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients diagnosed with foregut cancers who may face barriers to receiving guideline-concordant treatment based on their race or geographic location.

Not a fit: Patients with foregut cancers who are already receiving guideline-concordant treatment or those outside the targeted demographic may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve access to appropriate cancer treatments for underserved populations.

How similar studies have performed: Other research has shown success in addressing healthcare disparities through similar predictive modeling approaches, indicating potential for impactful outcomes in this area.

Where this research is happening

BIRMINGHAM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.