Predicting the risk of spine fractures in cancer patients after radiation treatment
Predicting Fracture Risk in Patients Treated with Radiotherapy for Spinal Metastatic Disease
This study is looking for a way to help cancer patients who have had radiation treatment for spine issues by predicting their risk of bone fractures, so they can get the right care before any problems happen.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10814861 on NIH RePORTER |
What this research studies
This research aims to develop a reliable method for predicting the risk of pathologic vertebral fractures in cancer patients who have undergone radiotherapy for metastatic spine disease. By utilizing advanced imaging techniques and analyzing bone structure and calcium content, the study seeks to identify patients at high risk for fractures before they occur. This proactive approach could lead to better management and treatment strategies tailored to individual patient needs, ultimately improving outcomes. The study will involve collecting clinical CT scans and serum samples from participants to assess their fracture risk.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients receiving radiotherapy for spinal metastatic disease.
Not a fit: Patients who are not undergoing radiotherapy for spinal metastatic disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of vertebral fractures in cancer patients, leading to improved quality of life and treatment outcomes.
How similar studies have performed: Previous research has shown promise in using imaging techniques to predict fracture risk, making this approach a continuation of established methodologies.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Alkalay, Ron N — Beth Israel Deaconess Medical Center
- Study coordinator: Alkalay, Ron N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.