Predicting the effectiveness of stem cells for treating lung injuries
A Clinical Indications Prediction (CLIP) Scale for Human Mesenchymal Stem Cells
['FUNDING_R01'] · UNIVERSITY OF FLORIDA · NIH-11056710
This study is looking at how to make stem cell treatments better for people with lung injuries by figuring out which donor cells work best for each patient, using special markers to guide the process.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-11056710 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the use of mesenchymal stem cells (MSCs) as treatments for various diseases, particularly acute lung injuries. It aims to develop a Clinical Indications Prediction (CLIP) scale that helps identify which donor stem cells are most effective for specific patient needs. By analyzing biomarkers like TWIST1, the study seeks to understand how donor characteristics influence the potency of stem cells. This could lead to more personalized and effective stem cell therapies for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients suffering from acute lung injuries who may benefit from stem cell therapies.
Not a fit: Patients with conditions unrelated to acute lung injuries or those who do not qualify for stem cell treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective stem cell treatments tailored to individual patient needs, improving outcomes for those with acute lung injuries.
How similar studies have performed: Previous research has shown promise in using biomarkers to enhance the effectiveness of stem cell therapies, suggesting that this approach could yield significant advancements.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PHINNEY, DONALD G — UNIVERSITY OF FLORIDA
- Study coordinator: PHINNEY, DONALD G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acute Lung Injury, Acute Pulmonary Injury