Predicting the cancer risk of pancreatic cysts using advanced imaging and biomarkers
Using Radiogenomics to Noninvasively Predict the Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas and Uncover Hidden Biology
This study is looking at new ways to use advanced imaging and blood tests to help predict if certain pancreatic cysts might turn into cancer, so patients can make better decisions about their care without needing invasive tests.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-10798763 on NIH RePORTER |
What this research studies
This research investigates how advanced imaging techniques and blood-based biomarkers can noninvasively predict the potential for pancreatic cysts, specifically intraductal papillary mucinous neoplasms (IPMNs), to become cancerous. By analyzing preoperative CT scans and incorporating artificial intelligence, the study aims to enhance the accuracy of predictions regarding the malignancy of these cysts compared to traditional methods. Patients may benefit from a more informed clinical decision-making process, potentially leading to better management of their condition without the need for invasive procedures.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been diagnosed with pancreatic cysts, particularly those suspected to be intraductal papillary mucinous neoplasms.
Not a fit: Patients with pancreatic cysts that are already confirmed to be benign or those with advanced pancreatic cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for identifying patients at risk of pancreatic cancer, allowing for earlier intervention and better outcomes.
How similar studies have performed: Previous research has shown promise in using imaging and biomarkers for cancer prediction, suggesting that this approach could lead to significant advancements in the field.
Where this research is happening
Tampa, United States
- H. Lee Moffitt Cancer Ctr & Res Inst — Tampa, United States (Active)
Researchers
- Principal investigator: Permuth, Jennifer B — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Permuth, Jennifer B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.