Predicting survival in patients with progressive lung disease

Survival prediction in patients with progressive fibrosing interstitial lung disease

NIH-funded research Massachusetts General Hospital · NIH-11109671

This study is looking at how advanced imaging and artificial intelligence can help doctors better predict how progressive fibrosing interstitial lung disease (PF-ILD) will affect patients, so they can make more informed treatment decisions and improve care for those living with this condition.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11109671 on NIH RePORTER

What this research studies

This research focuses on patients with progressive fibrosing interstitial lung disease (PF-ILD), a condition that leads to worsening lung function and high mortality. The study aims to develop an accurate prognostic prediction model using advanced imaging techniques and artificial intelligence to better understand individual patient outcomes. By analyzing high-resolution computed tomography (HRCT) images, the researchers hope to create a staging system that can guide treatment decisions and improve patient management. This approach seeks to address the current limitations in predicting disease progression and treatment efficacy.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with progressive fibrosing interstitial lung disease who are experiencing worsening symptoms and declining lung function.

Not a fit: Patients with stable interstitial lung disease or those not diagnosed with progressive fibrosing interstitial lung disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide patients with more accurate survival predictions, leading to better-informed treatment decisions and improved management of their condition.

How similar studies have performed: Previous research has shown promise in using imaging techniques and artificial intelligence for prognostic predictions in other lung diseases, suggesting potential success for this novel approach in PF-ILD.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.