Predicting protein function in eukaryotic parasites using advanced algorithms
A Structure-based orthology approach to predict protein function in eukaryotic parasites
['FUNDING_R21'] · SEATTLE CHILDREN'S HOSPITAL · NIH-11112406
This study is looking at how certain proteins in parasites work, which could help us find new ways to treat infections that affect many people around the world.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SEATTLE CHILDREN'S HOSPITAL (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-11112406 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the functions of proteins in eukaryotic parasites, which are responsible for various infectious diseases affecting millions globally. By utilizing advanced genome sequencing technologies and innovative algorithms, the project aims to accurately predict protein functions that have not been well characterized. The approach combines structural analysis with existing sequence data to enhance the annotation of proteins in a specialized database. This could lead to the identification of new therapeutic targets for treating infectious diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by infectious diseases caused by eukaryotic parasites.
Not a fit: Patients with non-infectious diseases or those not affected by eukaryotic parasites may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the understanding and treatment of infectious diseases caused by eukaryotic parasites.
How similar studies have performed: Other research has shown success in using structural approaches for protein function prediction, indicating a promising avenue for this novel methodology.
Where this research is happening
SEATTLE, UNITED STATES
- SEATTLE CHILDREN'S HOSPITAL — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PHAN, ISABELLE — SEATTLE CHILDREN'S HOSPITAL
- Study coordinator: PHAN, ISABELLE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Communicable Diseases