Predicting Preterm Birth in First-Time Mothers Using Cervical Imaging

Fully Quantitative Cervical Elastography for Prediction of Preterm Birth in Nulliparous Patients

NIH-funded research University of Michigan at Ann Arbor · NIH-11143738

This work aims to find a better way to identify first-time mothers who might deliver early by using a new ultrasound imaging technique on the cervix.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11143738 on NIH RePORTER

What this research studies

Preterm birth is a major concern for babies' health, and it's especially hard to predict in women having their first baby because there's no past history to guide doctors. Current methods, like measuring cervical length, don't work well for these mothers. This project uses a new, precise ultrasound imaging method called fully quantitative cervical elastography to measure the stiffness of the cervix. This advanced technique can accurately measure changes in the cervix, which could help doctors understand who is at higher risk for preterm birth.

Who could benefit from this research

Good fit: Ideal candidates for this research would be nulliparous patients, meaning women who are pregnant for the first time.

Not a fit: Patients who have previously given birth may not directly benefit from this specific prediction method, as it focuses on first-time mothers.

Why it matters

Potential benefit: If successful, this new imaging method could help doctors more accurately identify first-time mothers at risk for preterm birth, allowing for earlier interventions and better care.

How similar studies have performed: While cervical elastography is a promising technique, this specific approach introduces a novel quantitative measurement that overcomes limitations of previous non-quantitative systems.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.