Predicting outcomes of tuberculosis using genetic and biomarker information
Predicting tuberculosis outcomes using genotypic and biomarker signatures
['FUNDING_R01'] · TEXAS BIOMEDICAL RESEARCH INSTITUTE · NIH-10671340
This study is looking at how our genes and certain proteins can help us understand who might get tuberculosis (TB) and how it will affect them, using mice to find clues that could eventually help people get better care before they even show symptoms.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TEXAS BIOMEDICAL RESEARCH INSTITUTE (nih funded) |
| Locations | 1 site (SAN ANTONIO, UNITED STATES) |
| Trial ID | NIH-10671340 on ClinicalTrials.gov |
What this research studies
This research investigates how genetic factors and specific biomarkers can help predict the outcomes of tuberculosis (TB) in individuals. By studying a genetically diverse population of mice, researchers aim to identify genetic signatures and protein markers that indicate susceptibility or resistance to TB. The findings will be validated using human samples, with the goal of developing tools that can forecast disease onset before symptoms appear. This approach could lead to more effective diagnosis and treatment strategies for TB.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for tuberculosis, particularly those with a family history of the disease or other risk factors.
Not a fit: Patients who are not at risk for tuberculosis or who have already been diagnosed and treated may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for predicting and diagnosing tuberculosis, ultimately enhancing patient care.
How similar studies have performed: Previous research has shown promise in using genetic and biomarker approaches to predict disease outcomes, suggesting that this methodology could be effective.
Where this research is happening
SAN ANTONIO, UNITED STATES
- TEXAS BIOMEDICAL RESEARCH INSTITUTE — SAN ANTONIO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BEAMER, GILLIAN L — TEXAS BIOMEDICAL RESEARCH INSTITUTE
- Study coordinator: BEAMER, GILLIAN L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, neoplasm/cancer