Predicting outcomes of cardiac resynchronization therapy for heart failure patients
Multiscale Models for Predicting Short and Long-term Outcome of Cardiac Resynchronization Therapy
This study is looking at how to make heart treatments better for people with heart failure by using personalized computer models to plan the best way to place leads and set pacing, so the therapy works just right for each person.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-10899524 on NIH RePORTER |
What this research studies
This research investigates how to improve cardiac resynchronization therapy (CRT) for patients with heart failure and ventricular dyssynchrony. By using individualized computational models, the project aims to tailor CRT strategies to each patient's unique anatomy and condition, enhancing the effectiveness of the therapy. The approach involves virtual treatment planning to optimize lead placements and pacing protocols before actual implantation. This could lead to better patient outcomes by ensuring that CRT is more precisely aligned with each patient's needs.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients suffering from heart failure and experiencing ventricular dyssynchrony, particularly those with left bundle branch block.
Not a fit: Patients who do not have heart failure or ventricular dyssynchrony may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the effectiveness of cardiac resynchronization therapy, leading to better heart function and survival rates for patients with heart failure.
How similar studies have performed: Previous research has shown promise in using computational models for personalized treatment planning in cardiac therapies, indicating that this approach could be effective.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Bilchick, Kenneth C — University of Virginia
- Study coordinator: Bilchick, Kenneth C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.