Predicting Outcomes for Psychosis Using Health Records

4/5-Clinical Outcome Prediction of Psychosis from EHRs (COPPER)

NIH-funded research Feinstein Institute for Medical Research · NIH-11184442

This project uses artificial intelligence to help predict how psychosis might progress for individuals, aiming to improve personalized care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionFeinstein Institute for Medical Research NIH-funded
Lab location1 site (Manhasset, United States)
Project IDNIH-11184442 on NIH RePORTER

What this research studies

Many areas of medicine use tools to predict how a condition might unfold, but psychiatry currently has very few. This work aims to change that for psychosis-related disorders, which affect many people and have diverse long-term outcomes. We are building prediction tools using machine learning, combining information from long-term electronic health records, detailed patient characteristics, and genetic data. Our goal is to identify different patterns of outcomes among people with schizophrenia, which could lead to more tailored treatment plans.

Who could benefit from this research

Good fit: This work focuses on individuals with schizophrenia and psychosis-related disorders whose health information is available in large electronic health record databases.

Not a fit: Patients who do not have psychosis-related disorders or whose data is not part of the analyzed health record systems may not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to more personalized treatment plans, better monitoring of outcomes, and improved preventive care for individuals with psychosis.

How similar studies have performed: While clinical predictors are common in other medical fields, quantitative predictors for psychiatric decision-making are still very limited, making this a novel approach in psychiatry.

Where this research is happening

Manhasset, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.