Predicting outcomes for patients with pulmonary embolism using imaging and clinical data
Official title: Population-level Pulmonary Embolism Outcome Prediction with Imaging and Clinical Data: A Multi-Center Study
Funded at Stanford University · NIH-10914037 · Data updated 2026-11-12
This study is looking at ways to better treat pulmonary embolism (PE) by using computer technology to combine medical records and CT scan images, helping doctors identify patients who might be at higher risk and tailor their treatment for better outcomes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | August 1, 2021 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $406,141 |
| NIH project number | 5R01HL155410-04 |
| Project ID | NIH-10914037 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with pulmonary embolism who require risk assessment for treatment.
✕Less likely to help
Patients with pulmonary embolism who are not receiving treatment or those with very mild cases may not benefit from this research.
What this research studies
This research focuses on improving the treatment of pulmonary embolism (PE), a serious condition that can lead to death. By analyzing both clinical data from electronic medical records and imaging data from CT scans, the study aims to develop a method that can predict which patients are at high risk of poor outcomes. The approach utilizes advanced computer algorithms to combine these data sources, allowing for more accurate risk stratification at the point of care. This could lead to more personalized treatment plans and better management of PE cases.
Why it matters
Potential benefit: If successful, this research could significantly enhance patient safety and healthcare quality by providing tailored treatment strategies for those at high risk of complications from pulmonary embolism.
How similar studies have gone: Other research has shown promise in using similar data-driven approaches for predicting patient outcomes, indicating that this methodology could be effective.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Langlotz, Curtis P — Stanford University
- Study coordinator: Langlotz, Curtis P
Related research
Other NIH-funded projects on the same topics.
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AI-powered tool to better predict and manage acute pulmonary embolism
A new AI system uses imaging and patient data to improve how doctors predict short-term risk and tailor treatment for people with acute pulmonary embolism.
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Endovascular vortex ultrasound to treat blood clots in the lungs
A new therapy uses a tiny ultrasound device inside the blood vessels to rapidly dissolve clots in the lungs of people with pulmonary embolism, aiming to reduce the need for high doses of clot-busting drugs.
-
Supplemental Oxygen for Pulmonary Embolism: A Mechanistic Look at How Oxygen Helps the Heart and Lungs
This NIH grant tests how giving extra oxygen affects lung pressure and heart strain in people with acute pulmonary embolism, with supportive animal studies to understand the biology.
-
Pulmonary embolism: catheter-directed clot removal for better outcomes
This trial tests whether delivering clot-dissolving medication directly to the lungs via a catheter helps people with submassive pulmonary embolism feel better and function better, with fewer bleeding risks.
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Pulmonary embolism treatment with catheter-directed thrombus removal versus no catheter therapy
This study tests whether removing clot with a targeted catheter approach helps people with submassive pulmonary embolism feel better and move more easily, compared with not using catheter therapy.
-
Molecular and imaging study of blood clots and inflammation in pulmonary embolism
A research project uses a mouse model to understand how blood clots and inflammatory cells affect pulmonary embolism and its outcomes, with the goal of better diagnosis and treatment for people with PE.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.