Predicting Mood Swings in Bipolar Disorder
Predicting Recurrences in Bipolar Illness (Prompt-BD)
This project helps us understand and predict when mood changes might happen for young people and adults living with bipolar disorder.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11115782 on NIH RePORTER |
What this research studies
Living with bipolar disorder can be challenging, as each mood change can make the condition harder to manage and increase other health risks. Our team has developed a special calculator that can predict the likelihood of a mood change happening within the next 1 to 5 years for young people and adults with bipolar disorder. This project will help us confirm if this calculator works reliably for a wider group of individuals. We also want to learn how to predict mood changes in the shorter term, within 1 to 4 weeks, by looking at daily patterns like sleep, activity, and social interactions through smartphone apps. This personalized approach aims to help individuals get support sooner.
Who could benefit from this research
Good fit: Individuals who are youth or young adults living with bipolar disorder would be ideal candidates.
Not a fit: Patients whose condition is stable and not experiencing recurrences, or those outside the youth/young adult age range, may not directly benefit from this specific prediction tool.
Why it matters
Potential benefit: If successful, this work could allow for earlier interventions and more personalized treatment plans, potentially improving the lives of individuals with bipolar disorder.
How similar studies have performed: A risk calculator has been developed and shown promising results in initial testing, but this project aims to confirm its effectiveness in a new group of patients.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Birmaher, Boris — University of Pittsburgh at Pittsburgh
- Study coordinator: Birmaher, Boris
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.