Predicting Lung Changes in Sarcoidosis
Development of Clinical Prediction Models for Pulmonary Outcomes in Sarcoidosis
This project aims to create new tools that help doctors understand how lung sarcoidosis might progress for individual patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11078189 on NIH RePORTER |
What this research studies
Living with sarcoidosis can be challenging because it's hard to know if your condition will improve, stay the same, or worsen over time. This project seeks to develop better ways to predict how lung function might change in people with sarcoidosis, which can help doctors create more personalized care plans. Researchers will use existing clinical information and blood tests to build a prediction tool, and then see if adding new blood markers related to inflammation makes these predictions even more accurate. The goal is to provide doctors with practical tools they can use right away to improve long-term care for patients.
Who could benefit from this research
Good fit: This research is relevant for patients diagnosed with pulmonary sarcoidosis, especially those interested in how their disease might progress.
Not a fit: Patients without pulmonary sarcoidosis or those whose sarcoidosis affects other organs without lung involvement may not directly benefit from these specific prediction tools.
Why it matters
Potential benefit: If successful, this work could lead to earlier and more personalized treatment plans for people with pulmonary sarcoidosis, potentially preventing severe lung problems.
How similar studies have performed: Preliminary data has shown that certain blood markers can predict future declines in lung function, providing a foundation for this new model development.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Koth, Laura L — University of California, San Francisco
- Study coordinator: Koth, Laura L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.