Predicting long-term success of kidney transplants
Official title: Pretransplant comprehensive scores to predict long term graft outcomes
Funded at University of Maryland Baltimore · NIH-10810725 · Data updated 2026-11-12
This study is looking at how certain genes and blood markers can help predict how well kidney transplants will work in the long run, so we can better support patients and reduce the chances of transplant failure.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | March 16, 2023 |
| Project end | February 28, 2026 |
| Funding year | 2024 |
| Award (this year) | $232,512 |
| NIH project number | 5R21AI172077-02 |
| Project ID | NIH-10810725 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who are preparing to undergo kidney transplantation.
✕Less likely to help
Patients who have already received a kidney transplant and are experiencing chronic allograft dysfunction may not benefit directly from this research.
What this research studies
This research investigates how to predict the long-term success of kidney transplants by analyzing genetic and biological markers from both donors and recipients. It aims to identify specific gene signatures and blood profiles that can indicate the likelihood of graft survival after transplantation. By understanding the factors that contribute to chronic allograft dysfunction, the study seeks to improve patient outcomes and reduce the risk of transplant failure. The approach combines advanced genetic analysis with clinical data to create a comprehensive scoring system for pretransplant evaluation.
Why it matters
Potential benefit: If successful, this research could lead to better prediction of kidney transplant outcomes, ultimately improving patient survival rates and quality of life.
How similar studies have gone: Other research has shown promise in using genetic markers to predict transplant outcomes, indicating that this approach could be effective.
Where this research is happening
-
University of Maryland Baltimore
Baltimore, United States Active
Researchers
- Principal investigator: Mas, Valeria Raquel — University of Maryland Baltimore
- Study coordinator: Mas, Valeria Raquel
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.