Predicting liver health outcomes in children with nonalcoholic fatty liver disease
Predicting outcomes in nonalcoholic steatohepatitis with advanced fibrosis
This study is looking to find out how to spot kids with nonalcoholic steatohepatitis (NASH) who might face serious liver problems as their condition worsens, so doctors can help them early on.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project ID | NIH-10884404 on NIH RePORTER |
What this research studies
This research focuses on understanding how to predict serious liver-related health issues in children suffering from nonalcoholic steatohepatitis (NASH) as they develop fibrosis. By using advanced techniques such as MRI and various liver function tests, the study aims to identify children at high risk for complications like ascites and liver failure. The goal is to create a reliable scoring system that can help doctors determine which patients need early intervention and treatment. This innovative approach combines multiple health indicators to provide a comprehensive risk assessment.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-21 diagnosed with nonalcoholic steatohepatitis and showing signs of liver fibrosis.
Not a fit: Patients with liver diseases unrelated to nonalcoholic steatohepatitis or those without any signs of liver fibrosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies and treatments for children at risk of severe liver complications.
How similar studies have performed: Other research has shown promise in using advanced imaging and metabolic assessments to predict liver disease outcomes, suggesting that this approach could be effective.
Where this research is happening
Richmond, United States
- Virginia Commonwealth University — Richmond, United States (Active)
Researchers
- Principal investigator: Sanyal, Arun J — Virginia Commonwealth University
- Study coordinator: Sanyal, Arun J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.