Predicting how brain injuries affect recovery and independence
Official title: Predicting Dependency after Traumatic Brain Injury
Funded at Brigham and Women's Hospital · NIH-11049187 · Data updated 2026-11-12
This study is looking at how traumatic brain injuries affect a person's ability to live independently, using brain scans to find out which parts of the brain are involved, so we can better predict recovery and help patients and their families make informed treatment choices.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | April 1, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $227,707 |
| NIH project number | 5K23NS136767-02 |
| Project ID | NIH-11049187 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced a traumatic brain injury and are currently in the recovery phase.
✕Less likely to help
Patients with non-traumatic brain injuries or those who are not currently recovering from a brain injury may not benefit from this research.
What this research studies
This research investigates how traumatic brain injuries (TBI) impact a person's ability to function independently after the injury. By using advanced brain imaging techniques, the study aims to identify specific brain structures and networks that, when damaged, lead to dependency on caregivers. The goal is to improve the accuracy of predictions regarding recovery outcomes, which can help guide treatment decisions and support for patients and their families. The research will analyze data from various imaging modalities to enhance prognostic models for TBI.
Why it matters
Potential benefit: If successful, this research could lead to more accurate predictions of recovery outcomes for patients with traumatic brain injuries, ultimately improving their care and support.
How similar studies have gone: Other research has shown promise in using advanced imaging techniques to improve prognostication in brain injury cases, indicating that this approach may yield valuable insights.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Snider, Samuel — Brigham and Women's Hospital
- Study coordinator: Snider, Samuel
Related research
Other NIH-funded projects on the same topics.
-
AI-enhanced virtual reality tool to support remote emergency brain surgery training in Tanzania
A new AI-powered virtual reality tool helps non-experts in low-resource areas get real-time remote guidance for emergency traumatic brain injury surgery.
-
How head injury affects the heart and blood vessels
This project aims to find out whether traumatic brain injuries make people more likely to develop hardened arteries and heart problems, especially among veterans.
-
Neural targets for improving function in Veterans with alcohol use disorder and mild brain injury
This project tests a targeted brain-stimulation approach to help Veterans who have both alcohol use problems and mild traumatic brain injury improve daily functioning.
-
How head injuries affect the heart and blood vessels
This project is looking at whether past traumatic brain injuries cause changes in blood vessels and raise the risk of heart disease for people who have had head injuries.
-
Keeping oxygen in the injured brain after severe head trauma
This project uses a small brain oxygen monitor to guide ICU care for people with severe traumatic brain injury in hopes of improving recovery.
-
How head injuries affect Parkinson's over time
Researchers will follow people with Parkinson's disease to learn how past mild-to-moderate head injuries relate to thinking, mood, movement, brain changes, and quality of life.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.