Predicting health issues in very preterm newborns using metabolic profiling
Targeted metabolic profiling to predict major morbidity in very preterm newborns
This study is looking at how testing the metabolism of very premature babies—those born before 32 weeks—can help doctors predict and prevent serious health issues, like lung problems and bleeding in the brain, so they can provide better care for these tiny fighters.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Trustees of Indiana University NIH-funded |
| Lab location | 1 site (Bloomington, United States) |
| Project ID | NIH-10848429 on NIH RePORTER |
What this research studies
This research investigates how metabolic profiling can help predict serious health complications in very preterm newborns, specifically those born before 32 weeks of gestation. By analyzing metabolic status during routine newborn screenings, the study aims to identify infants at risk for conditions such as chronic lung disease, intraventricular hemorrhage, and other significant morbidities. The approach involves developing scoring systems that can effectively assess both mortality and morbidity risks, ultimately guiding treatment decisions and improving outcomes for these vulnerable infants.
Who could benefit from this research
Good fit: Ideal candidates for this research are very preterm newborns born before 32 weeks of gestation who are undergoing routine newborn screening.
Not a fit: Patients who are not very preterm newborns or those born after 32 weeks of gestation may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prediction and management of health complications in very preterm newborns, potentially reducing mortality and long-term disabilities.
How similar studies have performed: Previous research has indicated that metabolic profiling can be a promising predictor of neonatal outcomes, suggesting that this approach may yield significant insights.
Where this research is happening
Bloomington, United States
- Trustees of Indiana University — Bloomington, United States (Active)
Researchers
- Principal investigator: Ryckman, Kelli K. — Trustees of Indiana University
- Study coordinator: Ryckman, Kelli K.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.