Predicting breast cancer risk in women with benign breast conditions
Clinical breast cancer risk prediction models for women with a high-risk benign breast diagnosis
This study is looking at ways to help women with certain non-cancerous breast conditions understand their risk of developing breast cancer, so they can avoid unnecessary surgery if it's safe for them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Vermont & St Agric College NIH-funded |
| Lab location | 1 site (Burlington, United States) |
| Project ID | NIH-10931667 on NIH RePORTER |
What this research studies
This research focuses on developing clinical models to predict breast cancer risk in women diagnosed with high-risk benign breast conditions. It aims to identify which patients can safely avoid surgical excision, a common procedure currently performed to rule out cancer. By analyzing various patient, pathologic, and radiologic factors, the study seeks to provide evidence-based guidelines for managing these high-risk lesions. Ultimately, the goal is to enhance prevention and detection strategies for women who may not need aggressive treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are women who have been diagnosed with high-risk benign breast lesions following a core needle biopsy.
Not a fit: Patients with benign breast conditions that do not fall into the high-risk category may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could help reduce unnecessary surgeries and improve personalized care for women with benign breast conditions.
How similar studies have performed: Previous studies have shown promise in identifying risk factors for breast cancer in similar populations, but this research aims to provide more definitive evidence.
Where this research is happening
Burlington, United States
- University of Vermont & St Agric College — Burlington, United States (Active)
Researchers
- Principal investigator: Sprague, Brian L — University of Vermont & St Agric College
- Study coordinator: Sprague, Brian L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.