Predicting and preventing complications after surgery in older adults
Official title: Real-world and Innovative Multimodal Prediction and Prevention of Postoperative Mortality and Multi-morbidity
Funded at University of Pittsburgh at Pittsburgh · NIH-11128900 · Data updated 2026-11-12
This study is looking at how to keep older adults, especially those over 65, safer during and after surgery by finding out what might cause problems like confusion or other health issues, so we can come up with better ways to help them recover.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | June 1, 2025 |
| Project end | May 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $801,268 |
| NIH project number | 1R01AG085115-01A1 |
| Project ID | NIH-11128900 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 65 and older who are scheduled to undergo surgical procedures.
✕Less likely to help
Patients under the age of 65 or those not undergoing surgery may not benefit from this research.
What this research studies
This research focuses on understanding and addressing the risks faced by older adults undergoing surgery, particularly those over 65 years of age. It aims to identify factors that contribute to complications such as postoperative delirium, cognitive dysfunction, and increased mortality. By employing innovative multimodal prediction techniques, the study seeks to develop preventive strategies that can be implemented before and after surgery to improve patient outcomes. The research will analyze real-world data to create tailored interventions for this vulnerable population.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of postoperative complications and improve the quality of life for older surgical patients.
How similar studies have gone: Previous research has shown promising results in preventing postoperative complications in older adults, indicating that this approach could be effective.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Mahajan, Aman — University of Pittsburgh at Pittsburgh
- Study coordinator: Mahajan, Aman
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.