Precision Nutrition Program at UNC Chapel Hill

Nutrition for Precision Health: The University of North Carolina at Chapel Hill Clinical Center

NIH-funded research Univ of North Carolina Chapel Hill · NIH-11248410

This program will create personalized diet plans using genes, the microbiome, and health measures to help adults with or at risk for type 2 (adult-onset) diabetes.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-11248410 on NIH RePORTER

What this research studies

From your perspective, this program uses an anti-inflammatory Mediterranean-style diet as a starting point and gathers information about your genes, gut microbes, and other health traits to tailor nutrition. Meals may be prepared in clinical metabolic kitchens at UNC-NRI (Kannapolis) and UNC-Chapel Hill, and participants will be asked to provide biological samples and health measurements. The work is linked with the All of Us Research Program to combine broad participant data with local clinical testing. The goal is to learn which diet approaches best lower inflammation and improve health for different people.

Who could benefit from this research

Good fit: Adults (21+) with or at risk for adult-onset/type 2 diabetes, who can attend UNC clinical sites and provide health information and biological samples, are ideal candidates.

Not a fit: People with type 1 diabetes, children, or anyone unable to travel to the UNC sites or unwilling to provide samples or follow dietary guidance may not benefit from participating.

Why it matters

Potential benefit: If successful, this work could lead to diet recommendations tailored to your biology that reduce inflammation and lower diabetes risk or complications.

How similar studies have performed: Previous studies show Mediterranean-style diets can reduce inflammation and improve metabolic health, but using genetic and microbiome data to personalize diets is relatively new and still being tested.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.