Prebiotic vaginal lubricant to help prevent cervical cancer
Cervical Cancer Prevention Prebiotic Device
A preservative-free prebiotic vaginal lubricant designed to lower bacterial vaginosis and help reduce cervical cancer risk for adult women.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Glyciome, LLC NIH-funded |
| Lab location | 1 site (Valleyford, United States) |
| Project ID | NIH-11254991 on NIH RePORTER |
What this research studies
This project is developing PreBioGyn, a preservative-free prebiotic intravaginal lubricant you would use before sex to support healthy vaginal bacteria. The company plans to commercialize the device and run Phase II testing to confirm safety, effects on the vaginal microbiome, and suitability across reproductive life stages. Work includes refining the formula, measuring impacts on BV recurrence and microbial balance, and pursuing regulatory clearance for an over-the-counter lubricant claim. The goal is a first-in-class product you could use regardless of HPV vaccination status to improve vaginal health and potentially lower cervical cancer risk.
Who could benefit from this research
Good fit: Adult women (21+) who are at risk for or have a history of bacterial vaginosis and are interested in a preventive vaginal health product.
Not a fit: People with severe active infections requiring immediate antibiotic treatment, known allergies to product ingredients, or populations not studied (depending on trial inclusion) may not receive benefit.
Why it matters
Potential benefit: If successful, this product could reduce BV cases and recurrences, support a healthier vaginal microbiome, and ultimately lower long-term cervical cancer risk.
How similar studies have performed: Some probiotic and microbiome-focused approaches have shown mixed promise for BV, but a prebiotic intravaginal lubricant with these claims is a novel, early-stage approach.
Where this research is happening
Valleyford, United States
- Glyciome, LLC — Valleyford, United States (Active)
Researchers
- Principal investigator: Ellington, Joanna Elizabeth — Glyciome, LLC
- Study coordinator: Ellington, Joanna Elizabeth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.