Positive Peers mobile app to support young people with HIV

Randomized Control Trial of Positive Peers mHealth app as a clinic-based intervention to optimize HIV outcomes among young people with HIV

NIH-funded research Case Western Reserve University · NIH-11238924

This project sees if using the Positive Peers smartphone app together with local peer support helps people aged 13–34 living with HIV stay in care and reach viral suppression.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCase Western Reserve University NIH-funded
Lab location1 site (Cleveland, United States)
Project IDNIH-11238924 on NIH RePORTER

What this research studies

If you join, you'll use the Positive Peers app — a private smartphone program with wellness trackers, community forums, chat, blogs, and medication reminders — while clinic staff trained as peer administrators provide coaching and navigation. People aged 13–34 who are newly diagnosed, out of care, or not virally suppressed are randomly assigned to get the app plus usual care or to get usual care alone, and those who decline the app can join an observational group. The study runs through clinics in six U.S. Ending the HIV Epidemic jurisdictions and follows participants over time to measure clinic visits, medication adherence, app use, and viral load. Research staff will collect health records and app usage data to see whether the app-supported care leads to better HIV outcomes.

Who could benefit from this research

Good fit: Young people aged 13–34 with HIV who are newly diagnosed, out of care, or not currently virally suppressed are the intended participants.

Not a fit: People who are already consistently engaged in care with durable viral suppression, or who do not have reliable access to a smartphone, are unlikely to see added benefit from this app-based approach.

Why it matters

Potential benefit: If successful, the app could help more young people stay engaged in care and achieve viral suppression through peer support and practical self-management tools.

How similar studies have performed: Previous mobile health and peer-support programs have shown promise for improving HIV adherence and retention, but rigorous randomized trials focused on young people are still limited.

Where this research is happening

Cleveland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.