Population models to improve bladder cancer detection and control
Population Modeling of Bladder Cancer Detection and Control
['FUNDING_U01'] · BROWN UNIVERSITY · NIH-11142981
Using computer-based population models to find better ways to detect, prevent, and manage bladder cancer for people at risk or living with the disease.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BROWN UNIVERSITY (nih funded) |
| Locations | 1 site (PROVIDENCE, UNITED STATES) |
| Trial ID | NIH-11142981 on ClinicalTrials.gov |
What this research studies
The team is building computer models that combine information on who gets bladder cancer, risk factors like smoking and workplace exposures, results from new biomarkers, and outcomes of emerging treatments such as immunotherapy and antibody-drug conjugates. They will simulate different prevention, screening, and treatment strategies to estimate effects on survival, quality of life, and costs over time. The models rely on real-world patient data, public health records, and clinical results to make projections about population-level benefits. The goal is to point to practical changes in screening or care that could help people at risk or living with bladder cancer.
Who could benefit from this research
Good fit: People with bladder cancer or those at higher risk—such as older adults, current or former smokers, and individuals with occupational chemical exposures—are the most relevant to this work and could contribute data or join related efforts.
Not a fit: People without bladder cancer risk factors or with unrelated health conditions are unlikely to see direct benefits from this project.
Why it matters
Potential benefit: Could identify screening, prevention, or treatment approaches that reduce deaths, catch cancers earlier, and lower the overall cost of care for people with bladder cancer.
How similar studies have performed: Population-modeling has successfully guided screening and prevention choices for other cancers (for example, breast and colorectal), but applying these methods to bladder cancer with new biomarkers and treatments is relatively new.
Where this research is happening
PROVIDENCE, UNITED STATES
- BROWN UNIVERSITY — PROVIDENCE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TRIKALINOS, THOMAS — BROWN UNIVERSITY
- Study coordinator: TRIKALINOS, THOMAS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bladder Cancer, Breast Cancer, Cancer Cause, Cancer Causing Agents, Cancer Control