Point-of-care test to measure blood CPK for muscle and heart conditions
Official title: A point of care-device for the determination of creatinine phosphokinase (CPK), theCPK Now
Funded at Analytical Diagnostic Solutions, INC. · NIH-11419681 · Data updated 2026-11-12
A fast, easy home test is being developed to measure blood CPK levels so patients and clinicians can better manage muscle injuries, metabolic disorders, and acute heart conditions.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Analytical Diagnostic Solutions, INC. NIH-funded |
| Lab location | 1 site (Mount Laurel, United States) |
| Project start | September 20, 2023 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,095,992 |
| NIH project number | 5R44HD114325-03 |
| Project ID | NIH-11419681 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include individuals with LCFAODs, recent or ongoing muscle injury, or those at risk for heart or inflammatory muscle diseases who would benefit from at-home CPK monitoring.
✕Less likely to help
People without conditions affecting CPK levels or those unable to perform or access home testing may see limited benefit.
What this research studies
This project aims to create a simple at-home device that quickly shows how much CPK is in the blood, helping people monitor muscle health and metabolic problems. The test would be used by patients with muscle injury, metabolic disorders like LCFAODs, and conditions such as heart attack or inflammatory muscle diseases. The team plans to validate the device for accuracy and ease of use in real-world settings, with a focus on empowering patients to manage hydration, diet, activity, and medications. If successful, it could reduce hospital visits and support timely medical decisions.
Why it matters
Potential benefit: Users could rapidly track muscle and heart-related health changes to make informed care decisions at home.
How similar studies have gone: Previous reliance on centralized labs has shown CPK is a useful biomarker; this project seeks to bring rapid results to patients at home, which is a newer approach.
Where this research is happening
-
Analytical Diagnostic Solutions, INC.
Mount Laurel, United States Active
Researchers
- Principal investigator: Harper, Robert — Analytical Diagnostic Solutions, INC.
- Study coordinator: Harper, Robert
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.