NIH-funded research R21 grant

Planning to study geophagy in pregnant mothers and how it could affect children’s brain development

Official title: Planning Grant: Developing the Research Capacity to Investigate the Practice of Geophagy Among Pregnant Mothers and Impacts on Children's Neurodevelopment

Funded at Oregon State University · NIH-11418360 · Data updated 2026-11-12

This grant plans to build capacity to study how pregnant mothers eating earth in sub-Saharan Africa may influence their children’s neurodevelopment.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionOregon State University
NIH-funded
Lab location1 site (Corvallis, United States)
Project startSeptember 15, 2025
Project endJune 30, 2027
Funding year2026
Award (this year)$78,053
NIH project number5R21TW013293-02
Project IDNIH-11418360 on NIH RePORTER

Who could benefit from this research

Could help

HIV-negative peripartum mothers in sub-Saharan Africa and their children, with interest in participating in future studies on maternal geophagy and child development.

Less likely to help

Results may not directly benefit mothers or children in the immediate planning phase; the study emphasizes capacity building and methodology.

What this research studies

This planning grant aims to strengthen research collaboration between Oregon State University and partners in Ndola, Zambia, to measure how geophagy and exposure to heavy metals during pregnancy could affect a child's brain development. The team will train local researchers to use the Bayley Scales of Infant and Toddler Development to assess neurodevelopment in children. The project will enroll 200 HIV-negative peripartum mothers and examine geophagy practices, metal exposure, and potential effects on offspring development. The focus is on building local capacity and establishing methods for future, larger studies.

Why it matters

Potential benefit: If successful, this work could lead to better understanding of risks associated with geophagy during pregnancy and inform interventions to protect child neurodevelopment.

How similar studies have gone: Prior studies have linked maternal soil/clay ingestion to exposure to heavy metals and potential neurodevelopmental impacts, though this specific capacity-building planning grant is exploratory.

Where this research is happening

  • Oregon State University
    Corvallis, United States
    Active

Researchers

  • Principal investigator: Rothenberg, Sarah E — Oregon State University
  • Study coordinator: Rothenberg, Sarah E

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.