Pittsburgh Emergency Care Hub (SIREN)
Strategies to Innovate EmeRgENcy Care Clinical trials Network (SIREN) Network - Pittsburgh
This program helps run emergency medical trials and signs up patients to find faster, safer treatments for people with sudden, life‑threatening illnesses or injuries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11283977 on NIH RePORTER |
What this research studies
As a Pittsburgh hub for the SIREN network, the team enrolls patients across ambulances, emergency departments, intensive care units, and homes when time‑sensitive care is needed. They use special consent processes for emergencies and work to make joining a trial practical even when care must happen quickly. The site focuses on improving how people are recruited, how consent is handled, and how patient data stay accurate and usable. They also train early‑career investigators so more high‑quality emergency trials can run smoothly.
Who could benefit from this research
Good fit: Ideal candidates are people experiencing acute, time‑sensitive emergencies (for example severe trauma, cardiac arrest, stroke, or sepsis) who are treated by participating ambulance services or at participating hospitals.
Not a fit: People with stable, non‑emergency conditions or those not treated at participating sites are unlikely to be enrolled or directly benefit from this program.
Why it matters
Potential benefit: If successful, this work could speed development and delivery of better emergency treatments and make it easier for patients to access lifesaving care during crises.
How similar studies have performed: Emergency care research networks have previously run successful trials using similar hub-and-spoke and exception-from-consent approaches, and this effort builds on those established methods while refining recruitment and retention.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Callaway, Clifton W. — University of Pittsburgh at Pittsburgh
- Study coordinator: Callaway, Clifton W.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.