Physical resilience predicts healthier aging
Physical resilience is a predictor of healthy aging
['FUNDING_R01'] · UNIVERSITY OF WASHINGTON · NIH-11305312
This research looks at whether the body's ability to recover from physical stress predicts healthier aging in middle-aged and older people.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WASHINGTON (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-11305312 on ClinicalTrials.gov |
What this research studies
From my perspective as someone interested in aging, the team studies how well bodies bounce back from physical challenges using models that mimic real-life stressors. They give mice brief sleep disruption, a common chemotherapy drug, and small skin injuries, then track physical function, tissue changes, and aging-related signs. By grouping animals that resist or are susceptible to these stressors, they look for biological patterns tied to better recovery. The goal is to find targets that could later guide ways to help people keep function and age more healthily.
Who could benefit from this research
Good fit: Ideal candidates would be middle-aged or older adults interested in aging research or in ways to prevent age-related loss of function.
Not a fit: Younger people without aging-related concerns or patients whose conditions are unrelated to physical recovery may not benefit directly from this work.
Why it matters
Potential benefit: If successful, this work could reveal ways to strengthen recovery after physical stress and help people maintain function as they age.
How similar studies have performed: Earlier animal work from this group showed patterns linking stress responses to aging in mice, but translation to human health is still early.
Where this research is happening
SEATTLE, UNITED STATES
- UNIVERSITY OF WASHINGTON — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LADIGES, WARREN C — UNIVERSITY OF WASHINGTON
- Study coordinator: LADIGES, WARREN C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.