NIH-funded research R01 grant

Physical activity program for teens and young adults with congenital heart disease

Official title: Establishing Efficacy for the Congenital Heart Disease Physical Activity Lifestyle Intervention

Funded at Research Inst Nationwide Children's Hosp · NIH-11122224 · Data updated 2026-11-12

This program helps teens and young adults with congenital heart disease get more moderate-to-vigorous activity through tailored video coaching and activity tracking.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionResearch Inst Nationwide Children's Hosp
NIH-funded
Lab location1 site (Columbus, United States)
Project startSeptember 23, 2022
Project endJune 30, 2027
Funding year2025
Award (this year)$633,354
NIH project number5R01NR020423-04
Project IDNIH-11122224 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are 15–25-year-olds with moderate or complex congenital heart defects who can join live videoconference sessions and wear an activity monitor.

Less likely to help

Children under 15, people older than 25, those with very mild CHD, those already highly active, or anyone medically unable to exercise or to join video sessions may not gain benefit from this program.

What this research studies

You would join a 144-person trial for people ages 15–25 with moderate to complex congenital heart disease. The program uses live video sessions that teach goal-setting, self-monitoring, and skills tailored to your heart condition and activity needs. You will wear an accelerometer so the team can measure changes in moderate-to-vigorous physical activity and compare results to a control group. The researchers will also look at attitudes, social support, and perceived control to see how the program affects behavior and health.

Why it matters

Potential benefit: If successful, participants could increase regular physical activity and reduce long-term risk for hypertension and coronary artery disease.

How similar studies have gone: Earlier feasibility trials showed the program is doable and increased moderate-to-vigorous activity in less-active adolescents and young adults with CHD, but a larger trial is needed to confirm effects on activity and health.

Where this research is happening

  • Research Inst Nationwide Children's Hosp
    Columbus, United States
    Active

Researchers

  • Principal investigator: Jackson, Jamie L. — Research Inst Nationwide Children's Hosp
  • Study coordinator: Jackson, Jamie L.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.