Physical abilities and daily functioning in chronic kidney disease
Physical Function in Chronic Kidney Disease: Characterizing the Natural History and Relationship to Clinical Outcomes
['FUNDING_R01'] · UNIVERSITY OF PENNSYLVANIA · NIH-11143211
This project follows adults with chronic kidney disease to learn how their strength and ability to do daily tasks change over time.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PENNSYLVANIA (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-11143211 on ClinicalTrials.gov |
What this research studies
If I join, I'll be one of many adults with CKD who have regular checks of walking, strength, and other daily activities over several years. The team will track changes in physical function and connect them to outcomes like hospitalizations, quality of life, and transplant eligibility. They'll look for factors that make function worse earlier in the disease, including in younger adults and those not yet on dialysis. The goal is to find when and how to help people maintain independence and stay eligible for treatments like transplantation.
Who could benefit from this research
Good fit: Adults aged 21 and older with chronic kidney disease at any stage who can attend clinic visits and complete physical function tests are the best fit.
Not a fit: People without CKD or those unable to attend follow-up clinic visits or perform physical tests are unlikely to benefit directly from participation.
Why it matters
Potential benefit: This work could help spot early declines in physical function so patients get support or interventions sooner to stay independent and remain eligible for transplant.
How similar studies have performed: Prior research has linked poor physical function to worse outcomes in kidney failure, but few studies have tracked younger adults and earlier CKD stages over time, so this fills an evidence gap.
Where this research is happening
PHILADELPHIA, UNITED STATES
- UNIVERSITY OF PENNSYLVANIA — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SCHRAUBEN, SARAH JEANNE — UNIVERSITY OF PENNSYLVANIA
- Study coordinator: SCHRAUBEN, SARAH JEANNE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Chronic Renal Disease