Phone-based monitoring of heart filling pressure (LVEDP)
Official title: A mobile health framework for left ventricular end diastolic pressure diagnostics and monitoring.
Funded at Aventusoft, LLC · NIH-11138551 · Data updated 2026-11-12
A smartphone app paired with a small, non-invasive sensor to detect and track the pressure inside the heart’s left ventricle for people with or at risk for heart failure.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Aventusoft, LLC NIH-funded |
| Lab location | 1 site (Boca Raton, United States) |
| Project start | July 16, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $860,397 |
| NIH project number | 5R44HL167296-03 |
| Project ID | NIH-11138551 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with known or suspected heart failure, symptoms such as shortness of breath, or who are at high risk for elevated LVEDP would be the most likely candidates.
✕Less likely to help
People whose care requires immediate invasive catheter-based measurement in acute settings or whose symptoms are unrelated to ventricular filling pressure may not benefit from this device.
What this research studies
You would use an everyday smartphone and a lightweight, non-invasive cardiac sensor that connects to an app to estimate left ventricular end diastolic pressure (LVEDP). The system is being designed to give clinicians and you timely information about heart filling pressures without needing an echo or invasive catheter. The project focuses on making the technology cheap and easy to use at home or in primary care so it can help guide treatment and triage. Testing and development will include building the app, integrating the sensor, and validating measurements against standard clinical methods.
Why it matters
Potential benefit: If successful, this could allow earlier, simpler detection and home monitoring of high heart filling pressures, helping to prevent hospital visits and guide treatment decisions.
How similar studies have gone: Invasive pressure-monitoring devices have shown benefit for some patients, but smartphone-based, non-invasive LVEDP monitoring is a newer approach that is not yet widely proven.
Where this research is happening
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Aventusoft, LLC
Boca Raton, United States Active
Researchers
- Principal investigator: Kale, Kaustubh — Aventusoft, LLC
- Study coordinator: Kale, Kaustubh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.