Personalizing Immunotherapy for Lung Cancer Using Blood Tests and Imaging
Integrated blood and radiomic subtyping to guide immunotherapy treatment selection and early response assessment in metastatic non-small cell lung cancer
This research aims to find better ways to choose and monitor immunotherapy for people with advanced non-small cell lung cancer by looking at their blood and medical images.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11093994 on NIH RePORTER |
What this research studies
For patients with advanced non-small cell lung cancer, choosing the best immunotherapy can be challenging, and it's hard to know early on if the treatment is working. This project plans to develop new tools that combine information from simple blood tests and advanced medical imaging, like CT scans. By analyzing these details together, we hope to create personalized guides for doctors to select the most effective immunotherapy from the start. This approach could also help identify early signs of treatment success or failure, allowing for quicker adjustments to care.
Who could benefit from this research
Good fit: This research is most relevant to patients with metastatic non-small cell lung cancer who are considering or undergoing immunotherapy.
Not a fit: Patients without metastatic non-small cell lung cancer or those not receiving immunotherapy would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to more personalized and effective immunotherapy treatments for metastatic non-small cell lung cancer, potentially improving patient outcomes.
How similar studies have performed: While prior biomarker efforts have had limited success, the researchers have preliminary data demonstrating success using multi-modal approaches.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Vokes, Natalie — University of Tx Md Anderson Can Ctr
- Study coordinator: Vokes, Natalie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.