Personalizing electroconvulsive therapy for better outcomes in older adults with depression

Electroconvulsive therapy amplitude titration for improved clinical outcomes in late-life depression

NIH-funded research University of New Mexico Health Scis Ctr · NIH-11010854

This study is looking at how changing the strength of electroconvulsive therapy (ECT) can help older adults with depression feel better while reducing any memory issues, making the treatment more tailored to their needs.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of New Mexico Health Scis Ctr NIH-funded
Lab location1 site (Albuquerque, United States)
Project IDNIH-11010854 on NIH RePORTER

What this research studies

This research investigates how adjusting the intensity of electroconvulsive therapy (ECT) can improve treatment outcomes for older adults suffering from depression. Currently, ECT uses a fixed intensity that may not be suitable for everyone, especially considering the anatomical differences in older patients. By personalizing the amplitude of ECT, the study aims to enhance its effectiveness while minimizing cognitive side effects. The approach involves measuring how changes in amplitude affect brain plasticity and mood improvement.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults aged 50 and above who are experiencing depression and may benefit from electroconvulsive therapy.

Not a fit: Patients who are younger than 50 or those who do not have depression may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and safer ECT treatments for older adults with depression.

How similar studies have performed: Previous research has shown that personalized approaches in ECT can lead to improved outcomes, suggesting that this method may be effective.

Where this research is happening

Albuquerque, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.