Personalizing blood thinner use for older adults with heart rhythm issues

Individualizing Anticoagulant use in Older Adults with Atrial Fibrillation

['FUNDING_OTHER'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10917131

This study is looking to create a personalized way to choose blood-thinning treatments for older adults with atrial fibrillation, helping doctors make better decisions based on each person's unique health needs to reduce their risk of stroke.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorMASSACHUSETTS GENERAL HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10917131 on ClinicalTrials.gov

What this research studies

This research aims to tailor anticoagulant treatment for older adults with atrial fibrillation, a condition that increases the risk of stroke. The project will develop a model to predict the individual benefits and risks of anticoagulant therapy, addressing the current one-size-fits-all approach that may not be suitable for all patients. By analyzing clinical trial and observational data, the research seeks to provide personalized treatment recommendations that consider the unique health profiles of older adults. This approach aims to improve decision-making for high-risk patients who face significant therapeutic choices.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults diagnosed with atrial fibrillation who are considering anticoagulant therapy.

Not a fit: Patients who are not diagnosed with atrial fibrillation or who are younger and not at risk for stroke may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer and more effective anticoagulant use in older adults, reducing the risk of strokes while minimizing bleeding complications.

How similar studies have performed: Previous research has indicated the need for individualized treatment approaches in anticoagulation, suggesting that this tailored method could be a significant advancement in patient care.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.