Personalized vaccines targeting specific cancer antigens
NEOANTIGEN VACCINE CLINICAL TRIALS
This study is testing a special vaccine that’s made just for you to help your immune system fight your cancer by targeting unique markers found on your tumor, and it’s designed for people like you who are looking for personalized treatment options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Leidos Biomedical Research, INC. NIH-funded |
| Lab location | 1 site (Frederick, United States) |
| Project ID | NIH-10281326 on NIH RePORTER |
What this research studies
This research focuses on developing personalized neoantigen vaccines designed to stimulate the immune system to target and destroy cancer cells. By identifying unique antigens present on a patient's tumor, the vaccine aims to enhance the body's natural defenses against cancer. Patients will undergo a process to determine their specific neoantigens, followed by vaccination and monitoring for immune response and safety. The approach is innovative and seeks to provide a tailored treatment option for individuals with cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with cancer who have specific tumor antigens that can be targeted by a neoantigen vaccine.
Not a fit: Patients with cancers that do not express identifiable neoantigens or those who are not eligible for vaccination may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments that improve patient outcomes.
How similar studies have performed: Other research has shown promising results with personalized cancer vaccines, indicating potential for success in this approach.
Where this research is happening
Frederick, United States
- Leidos Biomedical Research, INC. — Frederick, United States (Active)
Researchers
- Principal investigator: Dmitrovsky, Ethan — Leidos Biomedical Research, INC.
- Study coordinator: Dmitrovsky, Ethan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.