Personalized Treatment for Thyroid Nodules
Official title: Thyroid Nodule Treatment Optimization: A Personalized Approach
Funded at Massachusetts General Hospital · NIH-11179274 · Data updated 2026-11-12
This project uses computer modeling to find the best ways to treat thyroid nodules and cancer, aiming to help many people in the U.S.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 1, 2019 |
| Project end | July 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $499,823 |
| NIH project number | 5R37CA231957-07 |
| Project ID | NIH-11179274 on NIH RePORTER |
Who could benefit from this research
✓Could help
This research is relevant for anyone with thyroid nodules or thyroid cancer, as it seeks to optimize treatment strategies for the general population.
✕Less likely to help
Patients whose thyroid nodule treatment decisions have already been made and completed may not directly benefit from this specific modeling project.
What this research studies
Thyroid nodules are common, and while many are harmless, some are cancerous, leading to a challenge in deciding the right treatment. This project aims to create a detailed computer model that simulates individuals with both benign and cancerous thyroid nodules across the U.S. population. By using this model, researchers hope to discover personalized treatment plans that are most effective for each patient. The goal is to avoid unnecessary treatments for those with less aggressive cancers while ensuring aggressive cancers are identified and treated appropriately.
Why it matters
Potential benefit: If successful, this work could lead to more precise and personalized treatment recommendations for thyroid nodules and cancer, potentially reducing overtreatment and improving patient outcomes.
How similar studies have gone: Few data exist on the impact of current clinical strategies for thyroid nodules, and conducting traditional clinical trials in this area is challenging, making this computer modeling approach a novel way to address the problem.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Cunningham, Carrie Elizabeth — Massachusetts General Hospital
- Study coordinator: Cunningham, Carrie Elizabeth
Related research
Other NIH-funded projects on the same topics.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.