Personalized treatment for seizures after cardiac arrest
Physiology-driven seizure management post-cardiac arrest
This study is looking at how to better manage seizures that happen after someone has a cardiac arrest by using special brain monitoring tools, and it's for patients who have experienced brain injuries from a lack of oxygen.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10997437 on NIH RePORTER |
What this research studies
This research focuses on improving the management of seizures that occur after cardiac arrest by using advanced brain monitoring technologies. The principal investigator, Dr. Edilberto Amorim, aims to identify specific biomarkers that indicate how well a patient's brain can recover from injury due to lack of oxygen. By analyzing large datasets of EEG and neuroimaging from over 1,500 subjects, the study seeks to find patterns in brain activity that can predict seizure control and neurological recovery. This personalized approach could lead to more effective treatment strategies for patients suffering from hypoxic-ischemic brain injury.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who have survived cardiac arrest and are experiencing seizures or seizure-like activity.
Not a fit: Patients who have not experienced cardiac arrest or do not have seizure activity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved seizure management and better neurological outcomes for patients who have experienced cardiac arrest.
How similar studies have performed: Previous research has shown promise in using advanced monitoring techniques to improve outcomes in similar patient populations, indicating that this approach could be effective.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Amorim, Edilberto — University of California, San Francisco
- Study coordinator: Amorim, Edilberto
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.