Personalized treatment decision tools for alcohol use disorder
Using patient-level decision modeling to improve use of treatments for alcohol use disorder
This project will build personalized decision models to help adults with alcohol use disorder and their doctors pick treatments that improve long-term health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-11125795 on NIH RePORTER |
What this research studies
If you have alcohol use disorder, researchers are making tools that use individual patient information to show likely long-term health outcomes of different treatment choices. They will combine existing patient data, clinical evidence, and decision-modeling methods to estimate how treatments (behavioral therapies, medications, and support groups) affect things like survival and liver health over time. The work aims to translate treatment effects into clear health benefits so clinicians are more likely to offer treatment and patients are more likely to try it. Findings could guide conversations between you and your clinician about realistic goals, including options other than complete abstinence.
Who could benefit from this research
Good fit: Adults aged 21 and older with alcohol use disorder who are considering treatment options are the ideal candidates to benefit from this work.
Not a fit: People without alcohol use disorder, those under age 21, or individuals needing only immediate emergency detox will not directly benefit from this grant's modeling work.
Why it matters
Potential benefit: If successful, this could increase use of effective AUD treatments and improve long-term health outcomes for people with alcohol use disorder.
How similar studies have performed: Decision modeling has informed care decisions in other conditions, but applying patient-level models specifically to boost treatment use for alcohol use disorder is relatively new.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Le, Phuc — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Le, Phuc
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.