Personalized treatment approaches for a rare type of Hodgkin lymphoma

Investigating personalized approaches to de-intensify therapy for nodular lymphocyte-predominant Hodgkin lymphoma

['FUNDING_CAREER'] · STANFORD UNIVERSITY · NIH-10948864

This study is looking to create personalized treatment plans for people with nodular lymphocyte-predominant Hodgkin lymphoma by examining their tumor and blood samples to find out which therapies might work best for them, helping to reduce side effects while still being effective.

Quick facts

Phase['FUNDING_CAREER']
Study typeNih_funding
SexAll
SponsorSTANFORD UNIVERSITY (nih funded)
Locations1 site (STANFORD, UNITED STATES)
Trial IDNIH-10948864 on ClinicalTrials.gov

What this research studies

This research focuses on developing personalized treatment strategies for patients with nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL). By analyzing tumor and blood samples, the study aims to identify specific genomic and microenvironmental factors that can predict how well patients will respond to different therapies. The approach combines expertise in cancer biology, biostatistics, and predictive modeling to optimize treatment plans, potentially reducing the intensity of therapy while maintaining effectiveness. Patients may benefit from a more tailored approach to their treatment, which could lead to fewer side effects and better outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with nodular lymphocyte-predominant Hodgkin lymphoma who are seeking personalized treatment options.

Not a fit: Patients with other types of Hodgkin lymphoma or those who do not have a diagnosis of lymphoma may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and less intensive treatment options for patients with nodular lymphocyte-predominant Hodgkin lymphoma.

How similar studies have performed: Previous research has shown promise in using genomic and microenvironmental factors to personalize cancer treatment, indicating that this approach could be beneficial.

Where this research is happening

STANFORD, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.