Personalized therapy for cystic fibrosis patients
Personalized Cystic Fibrosis Therapy and Research Center
['FUNDING_P30'] · CINCINNATI CHILDRENS HOSP MED CTR · NIH-10923858
This study is all about creating tailored treatment plans for people with cystic fibrosis by looking at their unique genes, especially to help improve the lives of CF patients, including those from minority backgrounds.
Quick facts
| Phase | ['FUNDING_P30'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CINCINNATI CHILDRENS HOSP MED CTR (nih funded) |
| Locations | 1 site (CINCINNATI, UNITED STATES) |
| Trial ID | NIH-10923858 on ClinicalTrials.gov |
What this research studies
This research focuses on developing personalized treatment plans for individuals with cystic fibrosis (CF) by analyzing the unique genetic variations in the CFTR gene that affect each patient. The approach includes collaboration across clinical, translational, and basic research to enhance therapy and improve the quality of life for CF patients, particularly those from minority populations. The study utilizes three integrated cores, including a new CF-Organ-on-a-Chip Core, to investigate the mechanisms of CF-related diabetes and optimize therapeutic outcomes while minimizing side effects.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cystic fibrosis, particularly those with specific genetic mutations affecting the CFTR gene.
Not a fit: Patients without a diagnosis of cystic fibrosis or those who do not have genetic variations in the CFTR gene may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and tailored treatments for cystic fibrosis, improving patient outcomes and quality of life.
How similar studies have performed: Previous research has shown promise in personalized medicine approaches for cystic fibrosis, indicating potential for success in this novel application.
Where this research is happening
CINCINNATI, UNITED STATES
- CINCINNATI CHILDRENS HOSP MED CTR — CINCINNATI, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NAREN, ANJAPARAVANDA P — CINCINNATI CHILDRENS HOSP MED CTR
- Study coordinator: NAREN, ANJAPARAVANDA P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.